How did Washington D.C.’s architect manage to aquire Karlsruhe’s city plan? Which daughter of an American president spent her schooldays in Karlsruhe? What forced a U.S. Secretary of the Interior to flee through a sewer in Rastatt? Where did Mark Twain leave his rheumatism? Why did the Titanic’s organ end up in Bruchsal? The answers plus additional information about the many-sided relations between the Karlsruhe region and the United States can be found in this unique German-American pocket book.